Applications Overview

The Firefly 3000 addresses a critical need among researchers of cancer, diabetes, and many other diseases by providing a unique window into cell signaling processes within tiny biological samples. While traditional analytical techniques such as Western Blots and mass spectrometry can consume 100,000 or more cells per measurement, Firefly 3000 assays can be run with as few as 25 cells. This capability enables protein analysis in many sample types previously considered much too small for protein analysis. A few representative examples of Firefly applications are:

• Phosphoprotein isoforms in cell lines
• Signaling proteins in sorted cells
• Drug actions in xenograft fine needle aspirates