Protein samples loaded onto a capillary are separated by isoelectric focusing, immobilized onto the capillary walls and then measured using chemiluminescent immunodetection.

Analyze low-abundance proteins in complex matrices
Cell Biosciences’ technology is the first practical improvement to the slow, qualitative process of Western blotting. By combining two orthogonal techniques, physical separation and specific antibody binding, the power of Western Blotting is retained while delivering orders-of-magnitude better quantitation, ease-of-use and throughput.

Western blotting remains a primary tool of life sciences laboratories today in spite of the manual nature and general limitations of the technique. The power of Western blotting is that it combines a separation step with antibody-probing; two very different mechanisms. This results in specificity of detection that is difficult to match, until the development of Cell Biosciences’ technology.

Major Advances in Biochemical Analysis

The Cell Biosciences’ technology promises to transform the way proteomics research is performed, as radically as the advances in genetic analysis technologies in the 1990’s transformed sequencing and gene expression research.